Anytime you are outside of a text input field in Karbon, press Alt (Windows) or Option (Mac) ahead of the following letters to perform the corresponding action:
Alt + C for a new Contact
Alt + E for a new Email
Alt + N for a new Note
Alt + W for a new Work item
Alt + S to open Global Search
Cntrl + Alt + T for a new Time Entry
Alt + T to start the Timer
After composing an email:
⌘ + Enter (Mac) / Ctrl + Enter (Windows) to send
Multi-select in Triage and My Week:
Select multiple items that are listed together in Triage or My Week. Hold Shift and select the top item, then the bottom item and all items in between will be selected as well.